The treatment of wastewater containing pharmaceuticals: Review
The massive production of pharmaceuticals and excessive consumption will lead to their leakage into various water sources. Conventional treatment methods have proven ineffective in the treatment of these contaminants. Thus, choosing the appropriate treatment method is extremely important to deal with these pollutants. This review presents an overview of pharmaceuticals in wastewater and studies the difference between the conventional and advanced oxidation processes (AOPs) for pharmaceutical treatment. AOPs can be an ideal solution for the degradation of these contaminants. The factors that affect the removal efficiency for AOPs were discussed, such as catalyst dose, initial concentration of contamination, pH of the solution, and hydrogen peroxide. The degradation pathway for some pharmaceuticals has also been discussed with oxidative species' role in the degradation operations.
Botero-Coy AM, Martínez-Pachón D, Boix C, Rincón RJ, Castillo N, Arias-Marín LP, et al. ‘An investigation into the occurrence and removal of pharmaceuticals in Colombian wastewater.’ Sci Total Environ [Internet]. 2018;642:842–53. Available from: http://dx.doi.org/10.1016/j.scitotenv.2018.06.088
Shraim A, Diab A, Alsuhaimi A, Niazy E, Metwally M, Amad M, et al. Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah. Arab J Chem [Internet]. 2017;10:S719–29. Available from: http://dx.doi.org/10.1016/j.arabjc.2012.11.014
Cuervo Lumbaque E, Lopes Tiburtius ER, Barreto-Rodrigues M, Sirtori C. Current trends in the use of zero-valent iron (Fe0) for degradation of pharmaceuticals present in different water matrices. Trends Environ Anal Chem. 2019;24.
Lin L, Wang H, Xu P. Immobilized TiO2-reduced graphene oxide nanocomposites on optical fibers as high performance photocatalysts for degradation of pharmaceuticals. Chem Eng J [Internet]. 2017;310:389–98. Available from: http://dx.doi.org/10.1016/j.cej.2016.04.024
Lin L, Wang H, Jiang W, Mkaouar AR, Xu P. Comparison study on photocatalytic oxidation of pharmaceuticals by TiO2-Fe and TiO2-reduced graphene oxide nanocomposites immobilized on optical fibers. J Hazard Mater [Internet]. 2017;333:162–8. Available from: http://dx.doi.org/10.1016/j.jhazmat.2017.02.044
Nebot C, Falcon R, Boyd KG, Gibb SW. Introduction of human pharmaceuticals from wastewater treatment plants into the aquatic environment: A rural perspective. Environ Sci Pollut Res. 2015;22(14):10559–68.
Sun J, Luo Q, Wang D, Wang Z. Occurrences of pharmaceuticals in drinking water sources of major river watersheds, China. Ecotoxicol Environ Saf [Internet]. 2015;117:132–40. Available from: http://dx.doi.org/10.1016/j.ecoenv.2015.03.032
Zhang H, Zhang P, Ji Y, Tian J, Du Z. Photocatalytic degradation of four non-steroidal anti-inflammatory drugs in water under visible light by P25-TiO2/tetraethyl orthosilicate film and determination via ultra performance liquid chromatography electrospray tandem mass spectrometry. Chem Eng J. 2015;262:1108–15.
Gar Alalm M, Tawfik A, Ookawara S. Enhancement of photocatalytic activity of TiO 2 by immobilization on activated carbon for degradation of pharmaceuticals. J Environ Chem Eng [Internet]. 2016;4(2):1929–37. Available from: http://dx.doi.org/10.1016/j.jece.2016.03.023
Rivera-Utrilla J, Sánchez-Polo M, Ferro-García MÁ, Prados-Joya G, Ocampo-Pérez R. Pharmaceuticals as emerging contaminants and their removal from water. A review. Chemosphere. 2013;93(7):1268–87.
Zupanc M, Kosjek T, Petkovšek M, Dular M, Kompare B, Širok B, et al. Removal of pharmaceuticals from wastewater by biological processes, hydrodynamic cavitation and UV treatment. Ultrason Sonochem. 2013;20(4):1104–12.
Delgado N, Navarro A, Marino D, Peñuela GA, Ronco A. Removal of pharmaceuticals and personal care products from domestic wastewater using rotating biological contactors. Int J Environ Sci Technol [Internet]. 2019;16(1):1–10. Available from: https://doi.org/10.1007/s13762-018-1658-2
Zorita S, Mårtensson L, Mathiasson L. Occurrence and removal of pharmaceuticals in a municipal sewage treatment system in the south of Sweden. Sci Total Environ [Internet]. 2009;407(8):2760–70. Available from: http://dx.doi.org/10.1016/j.scitotenv.2008.12.030
Gar Alalm M, Tawfik A, Ookawara S. Comparison of solar TiO2 photocatalysis and solar photo-Fenton for treatment of pesticides industry wastewater : Operational conditions , kinetics , and costs. J Water Process Eng. 2015;8:55–63.
Pourzamani H, Hajizadeh Y, Mengelizadeh N. Application of three-dimensional electrofenton process using MWCNTs-Fe3O4nanocomposite for removal of diclofenac. Process Saf Environ Prot. 2018;119:271–84.
Hassani A, Khataee A, Fathinia M, Karaca S. Photocatalytic ozonation of ciprofloxacin from aqueous solution using TiO2/MMT nanocomposite: Nonlinear modeling and optimization of the process via artificial neural network integrated genetic algorithm. Process Saf Environ Prot. 2018;116:365–76.
Azadi S, Karimi-Jashni A, Javadpour S. Modeling and optimization of photocatalytic treatment of landfill leachate using tungsten-doped TiO2 nano-photocatalysts: Application of artificial neural network and genetic algorithm. Process Saf Environ Prot [Internet]. 2018;117:267–77. Available from: https://doi.org/10.1016/j.psep.2018.03.038
Sopaj F, Oturan N, Pinson J, Podvorica F, Oturan MA. Effect of the anode materials on the efficiency of the electro-Fenton process for the mineralization of the antibiotic sulfamethazine. Appl Catal B Environ [Internet]. 2016;199:331–41. Available from: http://dx.doi.org/10.1016/j.apcatb.2016.06.035
Soleymani AR, Saien J, Chin S, Le HA, Park E, Jurng J. Modeling and optimization of a sono-assisted photocatalytic water treatment process via central composite design methodology. Process Saf Environ Prot. 2015;94(C):307–14.
Ong CB, Mohammad AW, Ng LY, Mahmoudi E, Azizkhani S, Hayati Hairom NH. Solar photocatalytic and surface enhancement of ZnO/rGO nanocomposite: Degradation of perfluorooctanoic acid and dye. Process Saf Environ Prot. 2017;112:298–307.
Yi Z, Wang J, Jiang T, Tang Q, Cheng Y. Photocatalytic degradation of sulfamethazine in aqueous solution using zno with different morphologies. R Soc Open Sci. 2018;5(4).
Cheng M, Zeng G, Huang D, Lai C, Xu P, Zhang C, et al. Hydroxyl radicals based advanced oxidation processes (AOPs) for remediation of soils contaminated with organic compounds: A review. Chem Eng J [Internet]. 2016;284:582–98. Available from: http://dx.doi.org/10.1016/j.cej.2015.09.001
Pal DB, Lavania R, Srivastava P, Singh P, Srivastava KR, Madhav S, et al. Photo-catalytic degradation of methyl tertiary butyl ether from wastewater using CuO/CeO2composite nanofiber catalyst. J Environ Chem Eng. 2018;6(2):2577–87.
Khavar AHC, Moussavi G, Mahjoub AR, Satari M, Abdolmaleki P. Synthesis and visible-light photocatalytic activity of In,S-TiO2@rGO nanocomposite for degradation and detoxification of pesticide atrazine in water. Chem Eng J. 2018;345(January):300–11.
Fouad K, Gar Alalm M, Bassyouni M, Saleh MY. A novel photocatalytic reactor for the extended reuse of W–TiO2 in the degradation of sulfamethazine. Chemosphere [Internet]. 2020;257:127270. Available from: https://doi.org/10.1016/j.chemosphere.2020.127270
Samy M, Ibrahim MG, Gar Alalm M, Fujii M, Ookawara S, Ohno T. Photocatalytic degradation of trimethoprim using S-TiO2 and Ru/WO3/ZrO2 immobilized on reusable fixed plates. J Water Process Eng. 2020;33(September 2019):3–10.
Gar Alalm M, Ookawara S, Fukushi D, Sato A, Tawfik A. Improved WO3 photocatalytic efficiency using ZrO2 and Ru for the degradation of carbofuran and ampicillin. J Hazard Mater. 2016;302:225–31.
Boczkaj G, Fernandes A. Wastewater treatment by means of advanced oxidation processes at basic pH conditions: A review. Chem Eng J [Internet]. 2017;320:608–33. Available from: http://dx.doi.org/10.1016/j.cej.2017.03.084
Lofrano G, Pedrazzani R, Libralato G, Carotenuto M. Send Orders for Reprints to firstname.lastname@example.org Advanced Oxidation Processes for Antibiotics Removal: A Review. Curr Org Chem. 2017;21:1–14.
Yadav MSP, Neghi N, Kumar M, Varghese GK. Photocatalytic-oxidation and photo-persulfate-oxidation of sulfadiazine in a laboratory-scale reactor : Analysis of catalyst support , oxidant dosage , removal-rate and degradation pathway. J Environ Manage [Internet]. 2018;222(January):164–73. Available from: https://doi.org/10.1016/j.jenvman.2018.05.052
Liu F, Liang J, Chen L, Tong M, Liu W. Photocatalytic removal of diclofenac by Ti doped BiOI microspheres under visible light irradiation : Kinetics , mechanism , and pathways. J Mol Liq [Internet]. 2019;275:807–14. Available from: https://doi.org/10.1016/j.molliq.2018.11.119
Ahmed S, Rasul MG, Martens WN, Brown R, Hashib MA. Heterogeneous photocatalytic degradation of phenols in wastewater: A review on current status and developments. Desalination [Internet]. 2010;261(1–2):3–18. Available from: http://dx.doi.org/10.1016/j.desal.2010.04.062
Qamar M, Saquib M, Muneer M. Photocatalytic degradation of two selected dye derivatives, chromotrope 2B and amido black 10B, in aqueous suspensions of titanium dioxide. Dye Pigment. 2005;65(1):1–9.
Karaca M, Kiranşan M, Karaca S, Khataee A, Karimi A. Sonocatalytic removal of naproxen by synthesized zinc oxide nanoparticles on montmorillonite. Ultrason Sonochem. 2016;31:250–6.
Kovacic M, Salaeh S, Kusic H, Suligoj A, Kete M, Fanetti M, et al. Solar-driven photocatalytic treatment of diclofenac using immobilized TiO2-based zeolite composites. Environ Sci Pollut Res [Internet]. 2016;23(18):17982–94. Available from: http://dx.doi.org/10.1007/s11356-016-6985-6
Malakootian M, Nasiri A, Amiri Gharaghani M. Photocatalytic degradation of ciprofloxacin antibiotic by TiO2 nanoparticles immobilized on a glass plate. Chem Eng Commun [Internet]. 2020;207(1):56–72. Available from: https://doi.org/10.1080/00986445.2019.1573168
Malakootian M, Mahdizadeh H, Dehdarirad A, Amiri Gharghani M. Photocatalytic ozonation degradation of ciprofloxacin using ZnO nanoparticles immobilized on the surface of stones. J Dispers Sci Technol [Internet]. 2019;40(6):846–54. Available from: https://doi.org/10.1080/01932691.2018.1485580
Karimnezhad H, Navarchian AH, Tavakoli Gheinani T, Zinadini S. Amoxicillin removal by Fe-based nanoparticles immobilized on polyacrylonitrile membrane: Individual nanofiltration or Fenton reaction, vs. engineered combined process. Chem Eng Res Des [Internet]. 2020;153:187–200. Available from: https://doi.org/10.1016/j.cherd.2019.10.031
Pretto PRP, Palácio SM, De Campos ÉA, Pazini CR, Veit MT. Sulfamethoxazole photocatalytic degradation in a continuous flow reactor using artificial radiation. J Environ Chem Eng. 2018;6(2):1926–33.
Píš͗ková V, Tasbihi M, Vávrová M, Štangar UL. Photocatalytic degradation of β-blockers by using immobilized titania/silica on glass slides. J Photochem Photobiol A Chem. 2015;305:19–28.
Horovitz I, Avisar D, Baker MA, Grilli R, Lozzi L, Di Camillo D, et al. Carbamazepine degradation using a N-doped TiO2 coated photocatalytic membrane reactor: Influence of physical parameters. J Hazard Mater [Internet]. 2016;310:98–107. Available from: http://dx.doi.org/10.1016/j.jhazmat.2016.02.008
Cassano AE, Alfano OM. Reaction engineering of suspended solid heterogeneous photocatalytic reactors. Catal Today. 2000;58(2):167–97.
Mahalakshmi M, Arabindoo B, Palanichamy M, Murugesan V. Photocatalytic degradation of carbofuran using semiconductor oxides. 2007;143(February 2006):240–5.
Shankar MV, Anandan S, Venkatachalam N, Arabindoo B, Murugesan V. Novel thin-film reactor for photocatalytic degradation of pesticides in an aqueous solution. J Chem Technol Biotechnol. 2004;79(11):1279–85.
Mirzaei A, Chen Z, Haghighat F, Yerushalmi L. Removal of pharmaceuticals and endocrine disrupting compounds from water by zinc oxide-based photocatalytic degradation: A review. Sustain Cities Soc [Internet]. 2016;27:407–18. Available from: http://dx.doi.org/10.1016/j.scs.2016.08.004
Patil AB, Patil KR, Pardeshi SK. Ecofriendly synthesis and solar photocatalytic activity of S-doped ZnO. J Hazard Mater [Internet]. 2010;183(1–3):315–23. Available from: http://dx.doi.org/10.1016/j.jhazmat.2010.07.026
Rabindranathan S, Devipriya S, Yesodharan S. Photocatalytic degradation of phosphamidon on semiconductor oxides. J Hazard Mater. 2003;102(2–3):217–29.