Journal of Infertility and Reproductive Biology

Subcutaneous Infiltration of Gentamycin Saline Solution to Reduce Rates of Cesarean Section Surgical Site Infection in Primigravidas Scheduled for Elective Cesarean Section

Mostafa Abdulla Elsayed Mahmoud — 2022-09-29

Cesarean section is a daily practice with the incidence in Egypt exceeding 40 percent, surgical site infection is uncommon morbidity, and efforts made extensively to lower the infection rate the presented work aimed at lowering surgical site infection in cesarean section with the use of gentamycin solution preclosure to reduce CS-SSI rates. The presented work was a controlled trial involving 200 cases of elective cesarean section done in Zinat Alhyat hospital for delivery in Benha city. Two hundred cases recruited from Zinat al-Hayat hospital in Benha were divided into two groups: group one [gentamycin group] hundred cases receiving pre-closure irrigation of the subcutaneous tissue with gentamycin vial 40mg diluted in 10 ml syringes then closing the wound with prolene sutures. Group 2 hundred cases not [control non-intervention] receiving gentamycin infiltration and taken as the control group the wound closed with prolene sutures without infiltration with gentamycin. Written consent was signed by all participants in the trial. The study gave the following. Cesarean section surgical site infection dropped from 8 percent in the control group to 1 percent in the trial group with gentamycin. Surgical site infection post-cesarean section can be reduced by subcutaneous infiltration with gentamycin saline solution.

male infertility: etiology & evaluation

Dr Rizwan Ali Lakho — 2022-09-20

Infertility is defined as the unable to conceive despite having one year of regular unprotected intercourse. It affects both genders globally. The increase in incidence is also due to delaying the start of families by many couples. Infertility is generally classified into two categories when a couple is unable to conceive after at least 1 year of unprotected sexual intercourse is termed primary, while any couple who has conceived previously but is not unable to conceive again is called secondary. The couple should consider the evaluation, if either partner has any known risk factor for infertility (e.g., advanced female age, male with a history of undescended testicles), or if the couple has concerns about their fertility potential. In most cases, it is recommended that both partners be evaluated simultaneously to prevent any delays in successful treatment. According to the WHO report on reproductive health, infertility may affect 15% of couples per year globally, of these, 20% will have a male factor that is solely responsible; male factors will contribute in an additional 30% of cases. When a man has any problem with his reproductive system it can lead to male infertility. Exposure to toxic substances, chemotherapy, radiation, and physical problems with the testes. Lifestyle, notably poor health habits and conditions (smoking, obesity, excessive alcohol consumption, use of drugs, testosterone, or anabolic steroids) may cause infertility in both sexes. Undescended testicle (cryptorchidism), Past inflammation of the prostate or past genital infections and/or high fever, Injury to or Torsion (constricted blood flow to a testicle), exposure to certain medications, pesticides, and other toxins, injury to the spinal cord, prostate surgery, hormone problems, genetic or chromosomal conditions testicular cancer, vasectomy, sexually transmitted diseases, varicocele (dilated veins in the scrotum), Ejaculatory disturbances Early or late puberty, Exposure of the genitals to high temperatures, Hernia repair can cause infertility.

Pericentric Inversion of Chromosome 9 in both partners of a non-consanguineous couple with spontaneous abortions

Rashmi Talwar — 2022-12-31

The balanced pericentric inversion of chromosome 9, inv(9) despite being considered a normal variant has been frequently observed and reported in individual partners with spontaneous abortions. To the best of our knowledge, we report the first case of this chromosomal abnormality in both partners of a non-consanguineous marriage. This report highlights that inv(9) in both partners may be leading to unbalanced rearrangements in the fetus thereby leading to spontaneous abortions.

Interaction of Parasitemia, Haemato-Biochemical Indices and Gross Reproductive Pathology of Rabbit Bucks Infected with Trypanosoma Brucei Brucei

Imaben Grace Opaluwa-Kuzayed — 2023-02-15

Abstract

This study was designed to determine the interaction between parasitaemia, haemato-biochemical indices and gross reproductive pathologies of 20 adult rabbit (bucks), experimentally infected with Trypanosoma brucei over a period of 12 weeks. Ten out of the 20 rabbit bucks were inoculated intraperitoneally with 1ml of saline diluted blood containing 1 x 10⁶ trypanosomes T. brucei brucei, while the remaining ten rabbit bucks were left uninfected. The infected rabbit bucks were monitored for nine weeks, while the others served as control post infection. Parasitaemia was present at day six in the group A animals with mean values of 2.90±0.31, after which there were fluctuations in the levels of parasitaemia. Peak parasitaemia was attained at day 10 post infection having mean value of 3.00±0.33. The overall mean parasitaemia was 1.99 ± 0.25. There was progressive decrease in PCV with mean values of 40.07 ± 0.49 % and 36.42 ± 1.15 % for the control and infected groups, respectively. Haemoglobin concentrations had mean values of 14.31 ± 1.01^ag/dl and 12.21 ± 0.39^bg/dl for the control and infected groups, respectively, while plasma protein concentrations of infected and control groups had mean values of 6.48 ± 0.08^a gms/100ml and 6.41 ± 0.17^b gms/100ml, respectively. The study revealed a significant decrease (p˂0.05) in haematological values and plasma protein concentrations of rabbit bucks infected with Trypanosoma brucei when compared to the control. It is therefore concluded that the metabolism and health status of rabbits infected with T. brucei brucei are altered which might lead to increased mortality, infertility and or sterility.