Semen Quality Parameters in Male Partners of Infertile Couples and Their Correlation with Socio-demographic Features in Rural Tertiary Care Center of Southern India: An Observational Study
Impact of Socio-demographic Features on male fertility
Abstract
Background: Infertility especially male factor infertility is on rising trend all over the world due to numerous factors including environmental, lifestyle factors, occupation related, faulty dietary habits, etc. Present study aims at establishing correlation between various demographic features of male partners of infertile couples with their semen analysis report. Methodology: Present retrospective observational study was conducted in the infertility clinic of rural tertiary care center of Southern India over one year (August 2019 to July 2020). A total of 114 male partners of infertile couples fulfilling the inclusion criteria were enrolled. The impact of socio-demographic features including age, BMI, occupation, religion, duration and type of infertility, history of addiction on semen parameters was studied. Results: Of 114 participants, 82 (71.9%) had primary infertility and 32 (28.1%) secondary. Of these 39(34.2%) had male factor infertility. The average (mean±SD) sperm concentration, total motility, dead and morphologically normal sperm of all participants were 47.51±37.5 million/ml, 46.96±22.8, 27.18±17.9 and 65.77±35.4 respectively. The most common abnormality on semen analysis was combination of different abnormalities (25.6%), followed by azoospermia (23.07%), oligozoospermia (17.9%) and teratozoospermia (17.9%). A significant inverse correlation was observed between body mass index and personal addiction with sperm motility. No significant correlation was found between male partner’s age, occupation, religion, duration and type of infertility with semen parameters. Conclusion: There are various modifiable factors that have an adverse impact on male fertility including smoking, alcohol, obesity, occupational exposure to heat and chemicals. Impact of male partners age on semen parameters could not be established.
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References
World Health Organization. Infertility: Fact sheets. September, 2020. Available at: https://www.who.int/news-room/fact-sheets/detail/infertility
Shah D. Expanding IVF treatment in India .............. need of the day!! J Hum Reprod Sci. 2017 Apr-Jun;10(2):69–70. doi: 10.4103/jhrs.JHRS_99_17.
WHO laboratory manual for the Examination and processing of human semen. Fifth Edition. 2010. World Health Organization Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland. Available at: https://www.who.int/docs/default-source/reproductive-health/srhr-documents/infertility/examination-and-processing-of-human-semen-5ed-eng.pdf
Agarwal A, Baskaran S, Parekh N, Cho CL, Henkel R, Vij S, et al. Male infertility. Lancet. 2021 Jan 23;397(10271):319-333. doi: 10.1016/S0140-6736(20)32667-2.
Patel AS, Leong JY, Ramasamy R. Prediction of male infertility by the World Health Organization laboratory manual for assessment of semen analysis: A systematic review. Arab J Urol. 2017;16(1):96-102. doi: 10.1016/j.aju.2017.10.005.
Toragall MM, Satapathy SK, Kadadevaru GG, Hiremath MB. Association of demographic and lifestyle factors with semen quality of men with fertility problems attending infertility center in North Karnataka. Indian J Med Spec 2019;10:79-83. Available at: http://www.ijms.in/text.asp?2019/10/2/79/258986
Ortega C, Verheyen G, Raick D, Camus M, Devroey P, Tournaye H. Absolute asthenozoospermia and ICSI: what are the options? Hum Reprod Update. 2011;17(5):684-92. doi: 10.1093/humupd/dmr018.
Dumont A, Barbotin AL, Lefebvre-Khalil V, Mitchell V, Rigot JM, Boitrelle F, et al. La necrozoospermie: du diagnostic étiologique à la prise en charge thérapeutique [Necrozoospermia: From etiologic diagnosis to therapeutic management]. Gynecol Obstet Fertil Senol. 2017;45(4):238-248. French. doi: 10.1016/j.gofs.2017.01.010.
Asha A. Impact of age, verified occupation and lifestyle on semen parameters of infertile males in Jaipur: A preliminary study. Int J Health Allied Sci 2014;3:278-83.
Gallo M, Licata E, Meneghini C, Dal Lago A, Fabiani C, Amodei M, et al. Impact of Paternal Age on Seminal Parameters and Reproductive Outcome of Intracytoplasmatic Sperm Injection in Infertile Italian Women. Front Endocrinol (Lausanne). 2019;10:35. doi: 10.3389/fendo.2019.00035.
Li WN, Jia MM, Peng YQ, Ding R, Fan LQ, Liu G. Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017. Reprod Biol Endocrinol. 2019;17(1):107. doi: 10.1186/s12958-019-0551-2.
Guo D, Wu W, Tang Q, Qiao S, Chen Y, Chen M, et al. The impact of BMI on sperm parameters and the metabolite changes of seminal plasma concomitantly. Oncotarget. 2017;8(30):48619-48634. doi: 10.18632/oncotarget.14950.
Belloc S, Cohen-Bacrie M, Amar E, Izard V, Benkhalifa M, Dalléac A, et al. High body mass index has a deleterious effect on semen parameters except morphology: results from a large cohort study. Fertil Steril. 2014;102(5):1268-73. doi: 10.1016/j.fertnstert.2014.07.1212.
Rufus O, James O, Michael A. Male obesity and semen quality: Any association? Int J Reprod Biomed. 2018;16(4):285-290. PMID: 29942937; PMCID: PMC6004593.
Thomsen L, Humaidan P, Bungum L, Bungum M. The impact of male overweight on semen quality and outcome of assisted reproduction. Asian J Androl. 2014;16(5):749-54. doi: 10.4103/1008-682X.125398.
Dai JB, Wang ZX, Qiao ZD. The hazardous effects of tobacco smoking on male fertility. Asian J Androl. 2015;17(6):954-60. doi: 10.4103/1008-682X.150847. PMID: 25851659; PMCID: PMC4814952.
Asare-Anane H, Bannison SB, Ofori EK, Ateko RO, Bawah AT, Amanquah SD, et al. Tobacco smoking is associated with decreased semen quality. Reprod Health. 2016;13(1):90. doi: 10.1186/s12978-016-0207-z.
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