Multifunctional Gold nanoparticle: as novel agents for cancer treatment

  • Masoomeh Yari Kalashgrani university of mohaghegh ardabili
  • Negar Javanmardi
Keywords: Nanoparticles; Cancer therapy; Gold


One of the most important problems in the therapy of cancer is that along with cancer cells, healthy cells are destroyed, for example, in radiation therapy, the radiation site can be more limited; However, radiation also damages some healthy cells, causing severe side effects for patients, so in recent years a method that can only target cancer cells has become one of the forefront of cancer research. Gold nanoparticles are one of the best drug delivery ever known. These gold particles are very small (one hundredth the size of a red blood cell) and can cross the body's natural and physiological barriers or hard tissues. Gold nanoparticles in cancer cells not only make it easier to image cancer cells, but they can also kill cancerous tumors by heating them. For the direct growth of gold nanoparticles inside a cancerous tumor, polyethylene glycol is used as the carrier of gold ions, which is essentially gold salt that dissolves in a liquid. When this carrier reaches the cancer cell, the cellular-acidic microenvironment converts gold from ionic to plasmonic gold nanoparticles. Another feature is the potential usefulness of gold nanoparticles, which can absorb light and then release energy in the form of heat. This property can make nanoparticles an ideal tool for accurate cancer therapy. Because gold nanoparticles can be purposefully inserted into cancer cells and then exposed to light, they can selectively kill cancer cells through thermal.


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How to Cite
Yari Kalashgrani M, Javanmardi N. Multifunctional Gold nanoparticle: as novel agents for cancer treatment. AANBT [Internet]. 20Jun.2022 [cited 18Aug.2022];3(01):43-8. Available from: