The role of Nanoparticles for Reactive Oxygen Species (ROS) in Biomedical Engineering


  • Sargol Mazraedoost Shiraz University of medical science
  • Reza Masoumzade Department of Medical, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Zahra Javidi Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Yousef Ashoori Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Keywords: Metal nanoparticles; Nanomaterials; Reactive oxygen species; Nanoscience; ROS Generation and Oxidative Stress


Among the greatest varied and cross-cutting features of biomedical nanotechnology applications is the synthesis, design, and characterization of novel nanomaterials. New developments in synthetics and engineering make it possible to produce an extensive variety of nanoparticles (NPs) and biocompatible nanostructured materials widely used in efficient diagnosis, drug delivery, and therapeutic procedures or deprived of other chemical and/or surface modifications of biomolecules. Because of their physical and chemical properties, metal-based nanoparticles (MNPs), as well as quantum dots (QDs), magnetic NPs, metal NPs, and metal oxide NPs, have a tremendous amount of power for biomedical applications. Nanoparticles (NPs) have superior (chemical and physical) features that create an ideal for different usages. Metallic NPs' structural modifications result in various biological activities, leading to diverse development capacities for reactive oxygen species (ROS). With chemistry, size, surface area, and particle shape, the amount of ROS provided by metallic NPs are correlated. In cell biology, ROS has many functions. ROS generation is a critical component in the toxicity caused by metallic NP and cellular signaling in cell differentiation, proliferation, and death.


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How to Cite
Mazraedoost S, Masoumzade R, Javidi Z, Ashoori Y. The role of Nanoparticles for Reactive Oxygen Species (ROS) in Biomedical Engineering. AANBT [Internet]. 1 [cited 23Sep.2021];:24-6. Available from: